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The Better Stack: Advanced DNA + microbiome testing with methylated supplements for a better you in 2025

The ultimate health optimisation bundle that combines genetic insights and microbiome analysis with targeted supplementation for enhanced resilience and longevity.

  • Comprehensive DNA reports covering methylation profile, nutrition, fitness, sleep and stress, and skincare genetic insights
  • Detailed microbiome analysis covering overall microbiome health, digestive health, gut-brain axis, and metabolism insights
  • One month's supply of MS-01 - our methylated B-complex supplement to support optimal health

Ultimate health optimisation bundle | Save 30% off PLUS free MS-01 supply

StrideDNA Optimal Health + StrideBiome Test Kit (50+ Reports)

$898 $628.60

Methylation profile, nutrigenetic, fitness, sleep, stress and skin reports + StrideBiome reports.


Money Back Made in the UK

What's included in The Better Stack?

Comprehensive DNA Testing

StrideDNA, our advanced at-home DNA test, analyses 9,000 essential genetic locations and 110 key genes, generating over 40 personalised genetic reports, covering:

  • Methylation Profile: Understanding your genetic capacity for key biological processes (e.g. Folate cycle and the MTHFR gene)
  • Diet & Nutrition: Personalised insights into your optimal diet, food sensitivities and micronutrient needs (e.g. Carb/fat sensitivities, vitamin B needs, lactose tolerance)
  • Fitness & Recovery: Exercise response and recovery optimisation markers (e.g. Power vs endurance, aerobic trainability, injury risk)
  • Sleep & Stress: Genetic factors affecting your rest and resilience (e.g. Chronotype, sleep quality, stress resilience)
  • Skin Health: Your genetic predisposition to various skin conditions and optimal care (e.g. Skin ageing, oxidative stress, pigmentation)



Each report includes practical, personalised recommendations to help you optimise your health based on your genetic profile.

Comprehensive DNA Testing

Advanced Microbiome Testing

StrideBiome, our in-depth at-home microbiome test, analyses your unique gut bacteria composition using next-generation sequencing technology, providing insights into:

  • Overall Gut Health: Understanding your microbiome diversity and beneficial bacteria balance (e.g. Microbiome health score, diversity index, bacterial richness and balance)
  • Digestive Function: Analysis of your digestive efficiency and nutrient absorption (e.g. Short-chain fatty acid production, gut barrier health, vitamin synthesis)
  • Gut-Brain Axis: The connection between your microbiome and mental wellbeing (e.g. Serotonin pathways, GABA production, dopamine synthesis)
  • Metabolic Health: Impact on your body's energy and weight management (e.g. Bacteroidota:Bacillota ratio, proteobacteria levels, metabolic markers)

Each report includes science-backed recommendations to help you nurture a healthier gut microbiome through targeted nutrition and lifestyle optimisation.

AdvancedMicrobiome Testing

Targeted Methylated Supplementation

MS-01, our premium methylated B-complex supplement, provides targeted nutritional support with active, bioavailable ingredients:

  • Optimised Methylation: Supporting those with genetic variations affecting nutrient processing (e.g. MTHFR gene variants, reduced methylation capacity)
  • Active B Vitamins: Premium blend of methylated B vitamins (e.g. Active B6, Methylfolate (B9), Methylcobalamin (B12))
  • Key Health Benefits: Support for multiple body systems (e.g. Energy production, nutrient absorption, neurotransmitter synthesis)

Each daily dose is formulated to complement your genetic and microbiome insights, supporting optimal:

  • Cellular health and nutrient utilisation
  • Mental wellbeing and cognitive function
  • Energy levels and physical vitality
  • Cardiovascular function
  • Immune system strength
Targeted Methylated Supplementation

Expert Health Consultation

Your bundle includes a personalised consultation with one of our dietetics experts to help you:

  • Interpret your results: Deep-dive into your DNA and microbiome reports to understand your unique health profile
  • Create your action plan: Develop a tailored nutrition and lifestyle strategy based on your genetic and gut insights
  • Optimise your supplements: Fine-tune your supplement regime to match your body's specific needs
  • Answer your questions: Get expert clarity on your results and recommendations in a one-to-one session

Our in-house experts specialise in personalised nutrition and can help translate your genetic and microbiome insights into practical, achievable changes for optimal health.

Expert Health Consultation

How it works.

Your journey to optimised health with Stride and The Better Stack.

Receive bundle & return your test samples

  • DNA and microbiome test kits + supplements delivered to your door
  • Collect your samples at home (cheek swab and stool sample)
  • Return both samples in pre-paid mailers and post

Get your personalised results

  • Comprehensive lab analysis of your DNA and gut bacteria
  • Access your detailed reports via your MyStride dashboard within 15 business days
  • Review your personalised lifestyle recommendations

Meet with one of our experts

  • One-to-one session with our registered dietetics experts
  • Deep dive into your results and recommendations
  • Discuss your personalised health optimisation plan

Why The Better Stack?

Our comprehensive health optimisation bundle combines genetic insights, microbiome analysis and targeted supplementation to help you understand and improve:

Longevity & Resilience

Unlock your genetic potential for healthy ageing while optimising your microbiome for long-term wellness. Understanding your methylation profile and gut health allows for targeted interventions that support cellular health and longevity pathways.

Sleep & Energy

Transform your daily vitality by understanding your genetic sleep patterns, stress response, and how your gut bacteria influence energy production.

Nutrition & Digestion

Understand your unique dietary needs through both genetic predispositions and gut bacterial composition. Get insights into nutrient absorption, food sensitivities, and personalised dietary recommendations for optimal health.

Cognitive Performance

Discover how your genes and gut bacteria affect your mental clarity, mood, and focus through key pathways like serotonin and GABA production.

Immune Function

Discover how your genetic profile and gut bacteria impact your immune response and inflammation levels.

Metabolic Health

Learn how your genes and microbiome influence your metabolism, weight management, and nutrient processing.

What our customers say...

2 weeks ago

Star Star Star Star Star

I thought it was so interesting and confirmed many things I already thought about myself but that doctors refused to look into. I took some of the recommendations and I am already starting to feel better. Highly recommend. The report was easy to read and I will definitely do again... Read More

I thought it was so interesting and confirmed many things I already thought about myself but that doctors refused to look into. I took some of the recommendations and I am already starting to feel better. Highly recommend. The report was easy to read and I will definitely do again next year to see if I am improving.

Renee W.

3 weeks ago

Star Star Star Star Star

I was thrilled to learn about Stride products and services. The vitamins arrived in a beautifully presented box which indicated a high level of quality and pride in their products. They are easy to take in their liquid form and have a nice flavor. I am greatly impressed with the... Read More

I was thrilled to learn about Stride products and services. The vitamins arrived in a beautifully presented box which indicated a high level of quality and pride in their products. They are easy to take in their liquid form and have a nice flavor. I am greatly impressed with the customer service department and how quickly they respond to my emails and their personalized service! I have recommended Stride to many friends and colleagues!

Tamara T.

4 weeks ago

Star Star Star Star Star

I have only used the product for the month , and very happy so far. Just changed to a quarterly subscription , So that’s a 5 stars for me.

I have only used the product for the month , and very happy so far. Just changed to a quarterly subscription , So that’s a 5 stars for me.

George William Robert B.

See all reviews

Our science, our lab.

Stride's diagnostic tests are developed by world-leading researchers and processed in our own UK laboratory. By eliminating third-party labs, we deliver faster results at better value, while constantly advancing our testing capabilities.

Discover more
Our science, our lab.

For the curious.

What is the StrideDNA Methylation Test and how can it benefit my health?

StrideDNA's Methylation Test is an advanced DNA screening test that provides insights into your genetic profile, nutrient deficiencies, and metabolic pathways. It helps you optimise your health by offering actionable and personalised recommendations based on your unique genetic makeup.

What is included with StrideDNA Methylation Test?

StrideDNA + Methylation Report includes

  • An easy-to-use at-home DNA test kit
  • Free return mailer to our UK based laboratory
  • 5 Methylation Reports with actionable insights:
    • Folate Cycle
    • Methionine Cycle
    • Transsulphuration Pathway
    • BH4 Cycle
    • Urea Cycle
  • 1:1 Health Expert Support (inc. Dietician)
  • Digital health platform

What is included with StrideDNA Methylation + Nutrigenetic Test?

StrideDNA + Methylation Report includes

  • An easy-to-use at-home DNA test kit
  • Free return mailer to our UK based laboratory
  • 5 Methylation Reports with actionable insights:
    • Folate Cycle
    • Methionine Cycle
    • Transsulphuration Pathway
    • BH4 Cycle
    • Urea Cycle
  • 24 Nutrigenetic Reports with actionable insights:
    • Carbohydrate Sensitivity
    • Saturated Fat Sensitivity
    • Vitamin A Needs
    • Vitamin B2 Needs
    • Vitamin B6 Needs
    • Vitamin B9 (folate) Needs
    • Vitamin C Needs
    • Vitamin B12 Needs
    • Vitamin D Needs
    • Vitamin E Needs
    • Iron Overload
    • Iron Deficiency
    • Antioxidants Needs
    • Omega 3 Needs
    • Lactose Intolerance
    • Coeliac Predisposition
    • Fructose Sensitivity
    • Salt Sensitivity
    • Alcohol Response
    • Caffeine Sensitivity
    • Detoxification Phase I
    • Detoxification Phase II
    • Sugar Preferences
    • Bitter Taste Perception
  • 1:1 Health Expert Support (inc. Dietician)
  • Digital health platform

What is included with StrideDNA Optimal Health Test?

StrideDNA + Methylation Report includes

  • An easy-to-use at-home DNA test kit
  • Free return mailer to our UK based laboratory
  • 5 Methylation Reports with actionable insights:
    • Folate Cycle
    • Methionine Cycle
    • Transsulphuration Pathway
    • BH4 Cycle
    • Urea Cycle
  • 24 Nutrigenetic Reports with actionable insights:
    • Carbohydrate Sensitivity
    • Saturated Fat Sensitivity
    • Vitamin A Needs
    • Vitamin B2 Needs
    • Vitamin B6 Needs
    • Vitamin B9 (folate) Needs
    • Vitamin C Needs
    • Vitamin B12 Needs
    • Vitamin D Needs
    • Vitamin E Needs
    • Iron Overload
    • Iron Deficiency
    • Antioxidants Needs
    • Omega 3 Needs
    • Lactose Intolerance
    • Coeliac Predisposition
    • Fructose Sensitivity
    • Salt Sensitivity
    • Alcohol Response
    • Caffeine Sensitivity
    • Detoxification Phase I
    • Detoxification Phase II
    • Sugar Preferences
    • Bitter Taste Perception
  • 4 Genetic Fitness Reports with actionable insights:
    • Power / Endurance
    • Aerobic Training Response
    • Recovery Efficiency
    • Injury Predisposition
  • 5 Genetic Mental Cognition (Sleep + Stress) Reports with actionable insights:
    • Genetic Chronotype
    • Sleep Quality
    • Caffeine & Sleep Response
    • Stress Tolerance
    • Warrior or Strategist
  • 7 Genetic Skin Reports with actionable insights:
    • Skin Ageing
    • Oxidative Stress Impact
    • Sensitivity to Refined Carbohydrate & Glycation
    • Pigmentation
    • Nickel Sensitivity
    • Detoxification
    • Skin Inflammation
  • 1:1 Health Expert Support (inc. Dietician)
  • Digital health platform

What methylation pathways does the StrideDNA Methylation Report include?

The StrideDNA Methylation Report includes a comprehensive analysis of over 9,000 genetic locations. It provides insights into key metabolic pathways such as the Folate Cycle, Methionine Cycle, Transsulphuration Pathway, BH4 Cycle, and Urea Cycle, helping you understand your methylation capabilities to optimise your health and wellness.

What genes / SNPs does the StrideDNA Methylation Report include?

StrideDNA Methylation covers the following well researched genes / SNPs:

BHMT: rs3733890
CBS: rs1801181
CBS (C699T): rs234706
COMT: rs4633, rs4680
DHFR: rs70991108
FUT2: rs601338
GSS: rs6088659
MAOA: rs6323
MAOB: rs1799836
MTHFD1: rs2236225
MTHFR (A1298C): rs1801131
MTHFR (C677T): rs1801133
MTR: rs1805087
MTRR: rs162036, rs1801394
NOS3: rs1799983
PEMT: rs7946
SOD2: rs4880
TCN2: rs1801198
VDR: rs1544410, rs731236

What is the StrideDNA Test?

StrideDNA is an easy-to-use at-home DNA test kit, designed to help you take more informed actions toward better health. The test kit includes step-by-step instructions for a quick DNA sample collection process. The kit includes a free return mailer envelope for you to post your sample to our UK-based lab. After 10 business days, you'll be notified via email that your results are ready to review on your my.getstride.com account.

How does StrideDNA differ from other DNA tests?

StrideDNA offers deeper analysis by examining more genetic locations than most methylation tests on the market (e.g. Gary Brecka's Health 10x test). It provides results through an interactive digital health platform and includes expert support from human health practitioners, ensuring you understand and can act on your results.

What kind of support does StrideDNA offer?

StrideDNA includes 1:1 consultations with expert dieticians and human health practitioners. The support covers functional nutrition, supplementation support, fitness optimisation, and holistic health practices to help you implement personalised health changes.

How quickly will I receive my StrideDNA test results?

With StrideDNA, you can expect to receive your test results within 10 business days. This fast turnaround is possible because Stride operates its own in-house laboratory in the UK, ensuring higher quality and industry-leading results delivery.

What makes methylation important for health?

Methylation is crucial for numerous body processes, including gene expression, energy production, fat metabolism, immune responses, detoxification, and neurotransmitter regulation. Proper methylation supports overall health, personalises nutritional choices and supplements, and helps prevent various chronic conditions.

How do genetic mutations affect methylation?

Genetic mutations, such as those in the MTHFR gene, can impair methylation, affecting the body's ability to convert nutrients effectively (e.g. folate). This can lead to issues like impaired immunity, fatigue, cardiovascular disease, neurological disorders, and mood disorders.

How do I get started with StrideDNA?

To get started with StrideDNA, choose your genetic insight level (Methylation only, Methylation + Nutrigenetic, or Methylation, Nutrigenetic, Fitness, Sleep + Stress, Skin Reports) and order your StrideDNA test kit. After returning your sample using the prepaid mailer, you'll receive your results and personalised health reports within 10 days.

Which countries do you ship StrideDNA Methylation Tests to?

At Stride, we strive to make our products accessible to customers worldwide. Currently, we offer shipping to the following countries:

United Kingdom:

As our main market, we offer expedited shipping and various delivery options across the United Kingdom.

Europe:

Albania
Andorra
Austria
Belarus
Belgium
Bosnia & Herzegovina
Bulgaria
Croatia
Cyprus
Czechia
Denmark
Estonia
Faroe Islands
Finland
Germany
Gibraltar
Greece
Guernsey
Hungary
Iceland
Ireland
Isle of Man
Italy
Jersey
Kosovo
Latvia
Liechtenstein
Lithuania
Luxembourg
Malta
Moldova
Monaco
Montenegro
Netherlands
North Macedonia
Norway
Poland
Portugal
Romania
Russia
San Marino
Serbia
Slovakia
Slovenia
Spain
Svalbard & Jan Mayen
Sweden
Switzerland
Ukraine
Vatican City

North America:

Canada
United States
Anguilla
Antigua & Barbuda
Aruba
Bahamas
Barbados
Belize
Bermuda
British Virgin Islands
Caribbean Netherlands
Cayman Islands
Costa Rica
Curaçao
Dominica
Dominican Republic
El Salvador
Greenland
Grenada
Guatemala
Haiti
Honduras
Jamaica
Mexico
Montserrat
Nicaragua
Panama
Sint Maarten
St. Kitts & Nevis
St. Lucia
St. Vincent & Grenadines
Trinidad & Tobago
Turks & Caicos Islands

Asia-Pacific:

Afghanistan
Armenia
Azerbaijan
Bahrain
Bangladesh
Bhutan
Brunei
Cambodia
China
Georgia
Hong Kong SAR
India
Indonesia
Iraq
Israel
Japan
Jordan
Kazakhstan
Kuwait
Kyrgyzstan
Laos
Lebanon
Macao SAR
Malaysia
Maldives
Mongolia
Myanmar (Burma)
Nepal
Oman
Pakistan
Palestinian Territories
Philippines
Qatar
Saudi Arabia
Singapore
South Korea
Sri Lanka
Taiwan
Thailand
Timor-Leste
Türkiye
Turkmenistan
United Arab Emirates
Vietnam
Yemen

Oceania:

Australia
Cook Islands
Fiji
French Polynesia
Kiribati
Nauru
New Zealand
Niue
Samoa
Solomon Islands
Tonga
Tuvalu

South America:

Argentina
Bolivia
Brazil
Chile
Colombia
Ecuador
French Guiana
Guyana
Paraguay
Peru
Suriname
Uruguay
Venezuela

Africa:

Algeria
Angola
Benin
Botswana
Burkina Faso
Burundi
Cameroon
Cape Verde
Central African Republic
Chad
Congo - Brazzaville
Congo - Kinshasa
Djibouti
Egypt
Equatorial Guinea
Eritrea
Ethiopia
Gabon
Gambia
Ghana
Guinea
Guinea-Bissau
Kenya
Lesotho
Liberia
Libya
Madagascar
Malawi
Mali
Mauritania
Mauritius
Morocco
Mozambique
Namibia
Niger
Rwanda
Senegal
Seychelles
Sierra Leone
Somalia
South Africa
Sudan
Togo
Tunisia
Uganda

Important Notes:

Shipping availability may vary based on product availability, regulatory restrictions, and other factors.
If your country is not listed, please reach out to our customer support team on hey@getstride.com for assistance.
Customs duties, taxes, and other fees may apply for international shipments. Customers are responsible for any additional charges incurred.
We continually strive to expand our shipping destinations to serve more customers worldwide. Keep an eye on our website for updates on new shipping locations.
If you have any questions or require further assistance regarding shipping destinations or delivery options, please don't hesitate to contact our customer support team on hey@getstride.com. We're here to help ensure a smooth and seamless shopping experience for you.

Why is the AHCY gene not included in Stride's Methylation report?

We rigorously select the genes included in our reports, each requiring evidence from human studies, reproducibility, and relevance to modifiable lifestyle changes. The AHCY gene, while important in certain contexts, is not included in our report for the following reasons:

Benign Variants: Two of the primary SNPs associated with the AHCY gene, rs41301825 and rs13043752, are now regarded as benign and have no significant effect. Additionally, these risk alleles are quite rare, with frequencies of 0.6% and 1.9% respectively, making them less relevant for the majority of our users.

Extremely Rare Mutation: The third variant, rs121918608, is not a typical SNP but rather a rare mutation associated with serious health conditions, including hypermethioninemia and severe developmental delays. Due to its rarity and the severity of its consequences, it is not suitable for inclusion in our reports.

Our goal is to provide genetic insights that are both meaningful and applicable to a broad audience. Including variants that are either benign or extremely rare with serious health implications would not align with our mission to deliver actionable and relevant information to our users.

Does Stride provide DNA testing for individuals under 18?

No, Stride does not provide DNA testing services for individuals under the age of 18. By placing a StrideDNA test order, activating a StrideDNA test, or accepting treatment, you confirm that you are the individual being tested, and that you are over 18 years old. If you have any questions about our services or need assistance, please feel free to contact our support team.